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冠状动脉性心脏病患者氧化低密度脂蛋白、基质金属蛋白酶-9及其基质金属蛋白酶组织抑制物-1的水平及临床意义 被引量:1

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摘要 研究发现,氧化低密度脂蛋白(ox-LDL)除了在动脉粥样硬化形成过程中发挥重要作用外,还可诱导多种基质金属蛋白酶(MMPs)的表达,参与细胞外基质降解、促进动脉粥样硬化斑块破裂。本研究通过联合检测不同类型冠状动脉性心脏病(冠心病)患者血中ox-LDL、MMP-9、基质金属蛋白酶组织抑制物-1(TIMP-1)水平的变化及其关系,进一步探讨临床识别和预测冠状动脉综合征(ACS)的血清学指标及斑块易损的机制。
出处 《上海医学》 CAS CSCD 北大核心 2008年第3期202-204,共3页 Shanghai Medical Journal
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