多普勒血流探测仪检测糖尿病下肢动脉病变的临床意义

The clinical value of the detection of peripheral arterial disease in type 2 diabetes mellitus patients with Doppler flow imaging survey meter

目的探讨踝肱指数（ABI）用于诊断2型糖尿病下肢动脉病变的临床意义及影响因素。方法应用ES-1000SPM多普勒血流探测仪检测110例2型糖尿病患者肱动脉、足背动脉或胫后动脉血流波形图及收缩压，根据ABI分为下肢动脉病变组（A组）和非下肢动脉病变组（B组），比较两组患者的临床资料并分析其危险因素。结果110例患者中，ABI小于0．9者20例，占18．2％。A组平均患者年龄、TC、LDL-C、24h尿微量白蛋白（24hUMA）、冠心病病史率均显著高于B组（P〈0．05），LDL-C、有冠心病病史为下肢动脉病变独立危险因素。结论测定糖尿病患者ABI可客观评价其下肢动脉功能状况，为临床治疗提供可靠依据，冠心病病史、高龄及高TC、LDL-C及24hUMA是下肢动脉病变的主要因素，且LDL-C和冠心病病史是独立危险因素。

Objective To assess the clinical significance of ankle-brachial index （ABI） in the diagnosis of peripheral arterial disease and its relationship with some interfering factors in type 2 diabetes mellitus. Methods One hundred and ten type 2 diabetes mellitus patients were soleeted. The systolic blood pressure and blood flow waveform in braehial artery, dorsal artery of foot or posterior tibial, artery were surveyed with Doppler flow imaging survey meter ES-1000 SPM. ABI was calculated and the patients were divided into peripheral arterial disease group （group A） and non-peripheral arterial disease group （group B）. Clinical data and risk factors were analyzed. Results In 110 patients, there were 20 cases （ 18.2% ） with ABI 〈 0.9. Age,TC ,LDL-C ,24 hours urinary mieroalbumin （24hUMA）and the prevalence of corofiary heart disease were all higher in group A than those in group B （P 〈 0.05）. LDL-C and the prevalence of coronary heart disease were independent risks variable for peripheral arterial disease. Conclusions ABI can assess objectively peripheral arterial disease in type 2 diabetes mellitus ,which offers reliable base to active therapy. Advanced age, hypereholesteremia and hyper 24hUMA are the main factors of peripheral, arterial disease.