男性慢性前列腺炎真菌感染耐药性研究

Study resistale of fungal infection in male chronic prostatitis

目的探讨本地区男性慢性前列腺炎感染真菌的分布规律及耐药性,为临床合理使用抗真菌药物提供依据。方法对临床慢性前列腺炎患者前列腺液真菌培养分离的菌株鉴定,用API-AUX20C真菌ID条板或RyidNicroscan真菌ID条板进行鉴定分型,纸片扩散法进行药敏试验。结果158株真菌中,白色念珠菌感染率高,占46·2%,热带念珠菌占30·4%,光滑念珠菌占13·3%,对5-氟胞嘧啶、氟康唑和咪康唑的耐药率很高,分别是22·2%、34·8%和25·3%。结论本地区慢性前列腺炎感染真菌分离率高,及时进行真菌的培养和药敏试验,对临床控制感染和合理使用抗真菌药物具有重要意义。

Objective To explore the region infected men with chronic prostatitis and the distribution of fungal resistance to the use of antifungal clinical reasonable basis. Methods Clinical prostatic fluid in patients with chronic prostatitis fungal strains isolated identification with APIAUX20C fungus ID of the fungus ID RyidNicroscan plate or identification of the plate type,disk diffusion method sensitivity test. Results 158 fungi, candida albicans infection rate high, accounting for 46.2%, candida tropicalis accounted for 30.4%, smooth candida albicans accounted for 13.3% ,5-fluorocytosine, the miconazole and fluconazole the high rate of drug resistance,namely 22.2% ,34.8% and 25.3%. Conclusion This fungal infection in chronic prostatitis high rate of separation, timely fungal culture and sensitivity test of the clinical infection control and rational use of antifungal drugs is of great significance.