盲人顶-枕皮质可塑性的脑神经机制

The Mechanism of Plasticity between Parietal and Occipital Cortex for the Blind

现代认知神经科学研究的主要目的是了解认知功能的神经机制,采用神经成像和无创性方法对盲人大脑皮质的实验,证实了盲人的枕叶皮质在盲文阅读时显著激活;经常进行盲文阅读的盲人手指有更大范围躯体感觉皮质表征;追踪空间触觉信息在皮质之间的加工轨迹的实验证明,皮质之间功能连通性有助于解释躯体感觉皮质-视皮质之间跨模块可塑性的神经机制。研究结果为我们提供了独特的机会来了解大脑皮层可塑性和行为补偿可能性的发生发展过程,并可能对重建某些丧失的功能和形成合适的教育策略提供有价值的参考。

The main aim of modem neuroscience is to know the mechanism of cognitive tasks. Functional neuroimaging and non - invasive methods are used and prove that the activation of occipital cortex is devoted to the Braille stimulation. In addition, a large area of the sematosensory cortex is devoted to the representation of reading finger in Braille readers. However, the functional connectivity underlying the enhanced eortio- cortical connectivity till the Transeranial Magnetic Stimulation is used to track the flow of spatial information between the related eortexes, which provides a unique opportunity to investigate how the regions of parietal and occipital cortex undergo cross - modal plasticity change as well as the behavioral compensation, and may have important implications for development of visual prosthesis and appropriate educational strategies.