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非环核苷膦酸酯类化合物Alamifovir(MCC-478)的合成 被引量:1

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出处 《贵州医药》 CAS 2008年第3期258-260,共3页 Guizhou Medical Journal
基金 贵阳医学院博士启动基金资助项目(C2006-7)
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参考文献5

  • 1Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures[J]. J Viral Hepat, 2004,11: 97-107.
  • 2Clercq ED. Strategies in the design of antiviral drugs. Nature Reviews[J]. Drug Discovery, 2002,1: 13-25.
  • 3Zoulim F. Assessing hepatitis B virus resistance in vitro and molecular mechanisms of nucleoside resistance[J]. Seminars in Liver Disease, 2002,22: 23-31.
  • 4Sekiya K, Takashima H,Ueda N. 2-Amino-6-arylthio- 9- [- 2- ( phosphono methoxy) ethyl-] purine Bis ( 2, 2, 2- trifluoroethyl) Esters as Novel HBV-Specific Antiviral Reagents[J]. Med Chem, 2002,45(14) : 3 138-3 142.
  • 5Choi JT, Hwang JR. Novel phosphonate nucleosides as antiviral agents[J]. Drugs of the Future, 2004,29(2): 163-177.

同被引文献9

  • 1LAVANCHY D. Hepatit is B virus epidemiology, disease hurden, treatment and current and emerging prevention and control meas- ures[J]. J ViraIHepat, 2004, 11(2) :97 -107.
  • 2DE CLERCQ E. Strategies in the design of antiviral drugs[J]. Nat Rev Drug Discov, 2002, 1 (1) :13 -25.
  • 3ZOULIM F. Assessing hepatitis B virus resistance in vitro and molecular mechanisms of nucleoside resistance [ J ]. Semin Liver Dis, 2002, 22(Suppl 1): 23 -31.
  • 4SEKIYA K, TAKASHIMA H, UEDA N, et al. 2-Amino-6-aryl- thio-9- [ 2- ( phosphonomethoxy ) ethyl ] purine bis ( 2,2,2-trifla- oroethyl) esters as novel HBY-specific antiviral reagents[ J]. J Med Chem, 2002, 45 ( 14 ) :3138 - 3142.
  • 5CHOI JT, H WANG JR. Novel phosphonate nucleosides as anti- viral agents[J]. Drugs Future, 2004, 29(2) :163 -177.
  • 6FISCHER KP, GUTFREUND KS, TYRRELL DL. Lamivudine resistance in hepatitis B: mechanisms and clinical in plications [J]. Drug Resist Update, 2001, 4(2): 118-135.
  • 7ONO-NITA SK, KATO N, SHIRATORI Y, et al. Novel nucleo-side analogue MCC-478 (LY582563) is effective against wild- type or lain ivudine resistant hepatitis B virus[ J].Antirnicrob A- gents Chemother, 2002, 46 ( 8 ) :2602 - 2605.
  • 8KAMIYA N, KUBOTA A, IWASE Y, et al. Antiviral activities of MCC-478, a novel and specific inhibitor of hepatitis B virus [ J]. Antimicrob Agents Chemother, 2002, 46 (9) :2872 - 2877.
  • 9王永广,何新华,仲伯华.阿米福韦类似物及其前药的设计、合成与生物活性[J].中国药物化学杂志,2010,20(6):484-489. 被引量:2

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