摘要
首次从药用植物美丽乌头(Aconitum pulchellum)中分离得到两个内酯型降二萜生物碱,通过波谱分析,其中1个鉴定为异叶乌头碱(heteratisine,1),另1个鉴定为二乙酰异叶乌头碱(diacetylheteratisine,2)。后者从自然界还是首次得到,其结构通过1的全乙酰化进一步得以确证。
Aconitum pulchellum Hand-Mazz, distributing in West of China, grows at an altitute about 3500-4500 m. Its roots have effects of activiting blood circulation and are employed to the treatment of rheumatic arthritis and some injuries. For the first time,two lactone-type norditerpenoid alkaloids, heteratisine(1) and diacetylheteratisine(2) ,were isolated and identified from the whole plants by spectral evidence and chemical transformation. Diacetylheteratisine was not report as natural product before.
出处
《天然产物研究与开发》
CAS
CSCD
1997年第1期1-3,共3页
Natural Product Research and Development
基金
中国科学院成都地奥科学基金
关键词
美丽乌头
药用植物
二萜生物碱
Aconitum pulchellum,diterpenoid alkaloid,diacetylheteratisine,heteratisine
