同种异体骨移植在特发重度僵硬性脊柱侧弯后路矫形融合术中应用

Application of allografts in managing severe and rigid idiopathic scoliosis

目的观察同种异体骨移植在特发性重度僵硬性脊柱侧弯后路矫形融合术中的应用疗效。方法实验组应用同种异体骨融合共30例，对照组应用自体骨共28例。对两组术后体温、血沉、切口反应和愈合情况，术后3、6个月脊柱融合情况进行对比、统计。结果随访平均6个月。术后体温、血沉和切口愈合情况两组间比较无明显差异；实验组有5例术后6～9d切口出现轻度红肿，无渗出，未行处置于第12天红肿消退；术后3个月X线片见植骨颗粒已经模糊；术后6个月见脊椎后弓结构已显示不清，为高密度骨覆盖。结论在特发性脊柱侧弯后路矫形融合术中，同种异体骨与自体骨移植具有同样的融合效果，并且可避免自体骨移植存在的不足，是一种安全有效的骨移植替代材料。

Objective To investigate the curative effect of allograft bone in posterior spinal fusion ior the patients with severe and rigid idiopathic scoliosis. Methods Thirty patients of idiopathic scoliosis received allograft bone in posterior spinal fusion for correction （experimental group）, while 28 patients received autogenous bone （control group）. Their clinical data were collected to analyze the body temperature, erythrocyte sedimentation rate before and after operation, healing of postoperative spinal incision. At 3 and 6 months after operation, foreign body reaction was studied clinically and fusion status was assessed radiographically. Results No significant foreign body reaction or chronic deep wound infection occurred in all patients. All patients got primary healing in 2 weeks, the new bone formed 3 months later and bone healing appeared radiographically 6 months later. Conclusion Allograft bone in the posterior spinal fusion for the patients of idiopathic scoliosis is matchable to autogenous bone, and it is safe and avoidance of the deficiency of autogenous bone.