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G蛋白基因多态性和心境障碍 被引量：2

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作者 李恒芬 谢光荣
机构地区 新乡医学院第二附属医院 中南大学湘雅二院精研所
出处 《临床心身疾病杂志》 CAS 2008年第2期179-180,183,共3页 Journal of Clinical Psychosomatic Diseases
基金 河南省教育厅科技攻关项目资助(2006320038)
关键词 心境障碍 G蛋白 基因多态性
分类号 R749.4 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献27

  • 1IB莱维坦,LK卡茨玛克.神经元:细胞和分子生物学[M].舒斯云,包新民,译.第1版.北京:科学出版社,2001:185-205
  • 2Mitchell PB, Manji HK. High levels of Gs alpha in platelets of euthymic patients with bipolar affective disorder[J]. Am J Psychiatry, 1997,154(2) : 218
  • 3A lda M. Is lithium response related to Gs alpha levels in transformed lymphoblasts form subjects with bipolar disorder? [J]. Affective Disord,2001,65(2) :117
  • 4Celaano E. Selectively regulation of presynaptic calcium 1 calmodulin-dependent predent protein dinase II by psychotic drugs[J]. Biol psychiatry, 2003,53 (3) : 442
  • 5Schreiber G,Avissar S. G proteins as a biochemical tool for diagnosis and monitoring treatments of mental disorders [J]. Isr Med Assoc J,2002:86
  • 6Levinson DF. The genetics of depression: a review[J].Biol Psychiatry,2006,60(2) : 84
  • 7Hayden EP,Nurnberger JI Jr. Molecular genetics of bipolar disorder[J].Genes Brain Behav, 2006,5 (1) : 85
  • 8胡健,胡友梅.G蛋白亚单位基因家族研究进展[J].生理科学进展,2003,34(2):131-135. 被引量：5
  • 9Willeit M,Praschak-Rieder N,Zill P,et al. C825T polymorphism in the G protein beta 3-subunit gene is associated with seasonal affective disorder[J]. Biol Psychiatry,2003,54 (7) :682
  • 10Bishop JR, Moline J, Ellingrod VL, et al. Serotonin 2A-1438 G/A and G-protein Beta 3 subunit C825T polymorphisms in patients with depression and SSRI-Associated sexual side-effects [J].Neuropsychopharmacology, 2006, 31 (10) :2281

二级参考文献26

  • 1Kozasa T, Itoh H, Tsukamoto T, et al . Isolation and characterization of the human Gsa gene. Proc Natl Acad Sci USA, 1988, 85 : 2081 -2085.
  • 2Hayward BE, Kamiya M, Strain L, et al. The human GNAS1 gene is imprinted and encodes distinct paternally and biallelically expressed G proteins. Proc Nail Acad Sci USA, 1998, 95 : 10038- 10043.
  • 3Zheng H, Radeva G, McCann JA, et al. Gαs transcripts are biallelically expressed in the human kidney cortex: implications for type pseudohypoparathyroidism type Ⅰ b. J Clin Endocrinol Metab, 2001, 86 : 4627 -4629.
  • 4Williamson CM, Skinner JA, Kelsey G, et al. Alternative non-coding splice variants of Nespas, an imprinted gene antisense to Nesp in the Gnas imprinting cluster. Mamm Genome, 2002, 13 : 74 -79.
  • 5Balcueva EA, Wang Q, Hughes H, et al. Human G protein γ11 and γ14 subtypes define a new functional subclass. Exp Cell Res, 2000, 257 : 310-319.
  • 6Hurowitz EH, Melnyk JM, Chen YJ, et al. genomic characterization of the human heterotrimeric G protein α ,β, and γ subunit Genes. DNA Res, 2000, 7 : 111 -120.
  • 7Watson A J, Aragay AM, Slepak VZ, et al. A novel form of the G protein β subunit Gβ5 is specifically expressed in the vertebrate retina. J Biol Chem, 1996, 271 : 28154 -28160.
  • 8Ray K, Robishaw JD. Cloning and sequencing of a rat heart cDNA encoding a G-protein β subunit related to the human retinal β3 subunit. Gene, 1994, 149 : 337 -340.
  • 9Vuoristo JT, Berrettini WH, Overhauser J, et al. Sequence and genomic organization of the human G-protein Golfalpha gene (GNAL) on chromosome 18p11, a susceptibility region for bipolar disorder and schizophrenia. Mol Psychiatry,2000, 5 : 495 -501.
  • 10Vuoristo Jr, Berrettini WH, Ala-Kokko L. C18orf2, a novel, highly conserved intronless gene within intron 5 of the GNAL gene on chromosome 18pll. Cytogenet Cell Genet,2001,93 : 19 -22.

共引文献9

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二级引证文献6

临床心身疾病杂志
2008年 第2期

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