2Krishtal OA,Pidoplichko VI. A receptor for protons in the nerve cell membrane[J]. Neuroscience, 1980,5(12) :2325
3Lingueglia E,Deval E,Lazdunski M. FMRF amide-gated sodium channel and ASIC channels : a new class of ionotropic receptors for FMRF amide and related peptides[J]. 2006,27 (5) : 1138
4Alvarez de la rosa D,Krueger S R,Kolar A,et al. Distribution,subeellular lacalization and ontogeny of ASIC in the mammalian central nervous system [J].Physiol, 2003, 546 (1):77
5Xiong ZG,Zhu XM,Chu XP,et al. Neuroprotection in ischemia:bloeking calcium-permeable acid-sensing ion channels [J]. Cell, 2004,118 : 687
6Simon RP, Griffiths T, Evans MC, et al. Calcium overload in selectively vulnerable neurons of the hippocampus during and after ischemia: an electron microscopy study in the rat[J]. Cereb Blood Flow Metab, 1984,4 : 350
7Kraig RP, Pulsinelli WA, Plum F. Hydrogen ion buffering during complete brain ischemia[J]. Brain Res, 1985, 342:281
8Nedergaard M, Kraig RP, Tanabe J, et al. Dynamics of interstitial and intracellular pH in evolving brain infarct[J].Am Physiol,1991,260:581
9Back T,Hoehn M,Mies G,et al. Penumbral tissue alkalosis in focal cerebral ischemia:relationship to energy metabolism,blood flow, and steady potential [J]. Ann Neurol, 2000,47:485
10Benveniste M, Dingledine R. Limiting stroke-induced damage by targeting an acid channel[J]. Med, 2005,352:85