B型利钠肽在非ST段抬高急性冠脉综合征早期危险分层的研究

Study on BNP for Early Risk Stratification of Patients with Acute Coronary Syndrome of Non-ST-Segment Elevation

【目的】探讨B型利钠肽(BNP)在非ST段抬高急性冠脉综合征早期危险分层的作用,以便发现高危患者。【方法】2007年1月至2007年7月就诊于中国医科大学附属盛京医院的非ST段抬高急性冠脉综合征患者62例,检测血浆BNP值,并行冠状动脉造影对冠脉病变进行评估,所有患者进行为期60d的随访。【结果】BNP升高组患者与多支血管病变和较差预后相关。【结论】BNP检测在急性冠脉综合征早期危险分层中起重要作用,BNP能提供较多的预后信息。

[Objective]To investigate the role of brain natriuretic peptide （BNP） in early risk stratification of patients with acute coronary syndrome of non-ST-segment elevation, and to find the patients with high risks. [Methods] The level of BNP in 62 patients with acute coronary syndromes of non-ST elevation from Jan. 2007 to Jul. 2007 in the Shengjing Hospital Affiliated to China Medical University were measured, and the lesion extent of coronary artery was assessed by angiography. Sixty-day follow-up was performed for all patients. [Results]The higher BNP level in patients was related to multivessel coronary artery disease and poor prognosis（ P 〈0.05）. [Conclusion]The measurement of BNP is available for the early risk stratification of patients with acute coronary syndrome of non-ST elevation. Early BNP measurement could provide more prognostic information.