小梁切除术+丝裂霉素C治疗青光眼的临床效果及对包裹囊状泡发生的影响

Observation on the Clinical Effect of Trabeculectomy Combined with Mitomycin C for the Treatment of Glaucoma and the influence on Tenon's Capsule Cysts

【目的】观察小梁切除术+丝裂霉素C(MMC)治疗青光眼对包裹囊状泡发生的影响。【方法】对64例均为单眼行抗青光眼手术,随机分为甲组(小梁切除术组)和乙组(小梁切除术+MMC组)各32例,术后随访6～18个月,对两组术后包裹囊状泡发生情况进行观察。【结果】64例青光眼患者中,甲组发生包裹囊状泡8例(25.0%),乙组4例(12.5%)(P<0.01)。【结论】小梁切除术联合应用MMC能有效减少抗青光眼手术包裹囊状泡的发生。

[Objective]To observe the effect of trabeculectomy combined with mitomycin C （MMC） for the treatment of glaucoma and the influence on Tenon＇s capsule cysts after therapy. [Methods] Sixty four cases undergoing monocular glaucoma surgery were randomly divided into Group A （trabeculectomy, n ： 32） and Group B （trabeculectomy ＋ MMC, n =32）. All patients were followed up for 6 to 18 months. The effect on Tenon＇s capsule cysts after glaucoma surgery was observed. [Results] After surgery, eight cases （25.0%） occurred Tenon＇s capsule cysts in Group A, but four cases （12.5%） in Group B（ P 〈0.01）. [Conclusion]Trabeculectomy combined MMC can be effective in reducing the incidence of Tenon＇s capsule cysts after glaucoma surgery.