腮腺多形性腺瘤手术后复发相关因素分析

Correlative Factors About the Post-operative Recurrence of Pleomorphic Adenoma in Parotid Gland.

目的本丈通过对594例患者进行回顾，分析腮腺多形性腺瘤术后复发的相关因素。方法对594例多形性腺瘤进行回顾及随访调查，结合患者发病年龄，肿瘤部位、大小，组织学形态及手术方式，统计描述术后复发的原因。结果594例患者中，术后复发36例，复发率为6．1％，肿瘤包膜完整的术后复发率为1．5％，包膜不完整的复发率为35％，统计学有显著差异（P〈0．01）。深叶肿瘤的术后复发率较浅叶肿瘤的复发率高，分别为22％及4％，肿瘤加腮腺浅叶切除术后的复发率低于肿瘤加腮腺全切除术后的复发率。结论影响腮腺多形性腺瘤术后复发的相关因素有：肿瘤的组织病理学特征、肿瘤的发生部位及手术方式，强调严格遵守无瘤的操作原则，首次手术彻底切除至关重要。

Objective To discuss the correlative factors of recurrence ofpleomorphic adenoma ofparotid gland though the retrospective study consisted of 594 patients. Methods A retrospective and follow-up study was conducted, with patients age at time of treatment, primary tumor location and size reviewed, to find out the reasons of pleomorphic adenoma of parotid gland recurrence, Results Of the 594 patients, 36（6.1%） were recurrent cases, the recurrence rates were different between cases with complete encapsulation（1.5%） and those without（35%）（P〈0.01）, Tumors arised from the deep lobe had a higher recurrence rate（22%） than those arised from superficial lobe（4%）. Conclusion The correlative factors of recurrences of pleomorphic adenoma of parotid gland are： Histological and Pathological features, primary location and surgical method. It＇s essential to strictly obey the surgical rules and perform complete exicision of tumor to decrease the recurrence rate.