复方银屑颗粒治疗小鼠银屑病模型的实验研究

Experimental Research on "Compound Yinxie Granule" in Treating Mice Psoriasis

目的:探讨复方银屑颗粒对小鼠银屑病模型的治疗作用。方法:小鼠灌服给予复方银屑颗粒后,观察药物对小鼠阴道上皮细胞有丝分裂以及鼠尾鳞片表皮颗粒细胞数的变化。结果:复方银屑颗粒能明显降低小鼠阴道上皮细胞有丝分裂、促进鼠尾表皮颗粒细胞形成。结论:复方银屑颗粒对小鼠银屑病模型有较好的治疗作用。

Objective： To investigate the effects of ＂Compound Yinxie Granule＂ on mice psoriasis. Methods： After oral administration of ＂Compound Yinxie Granule＂, its therapeutical effects against psoriasis were observed with animal models of vaginal epithelium cell mitosis and scaled tail epidermis in mice. Results： ＂Compound Yinxie Granule＂ could inhibit the mitosis of mouse vaginal epithelia, and promote the formation of cuticular granular cells on scaled epidermis of mouse tail significantly. Conclusion： ＂Compound Yinxie Granule＂ exhibits a beneficial influence on mice psoriasis.