加味二仙汤结合抗生素治疗中老年女性慢性尿路感染的疗效观察

Clinical Observation of Modified "Erxian Decoction" plus Antibiotics in Treating Chronic Urinary Tract Infection in Middle-aged and Old Women

目的观察加味二仙汤结合抗生素治疗中老年女性慢性尿路感染的临床疗效。方法将52例中老年女性慢性尿路感染患者(肾阳不足、余邪未清型)随机分为两组,每组各26例。对照组予敏感抗生素,足量14d;缓解期每晚临睡前服用单剂量抗生素1次。治疗组除选用敏感抗生素外,再予加味二仙汤。两组均2周为1个疗程,治疗3个疗程。观察患者治疗前后近期疗效,并随访6个月观察远期疗效与复发情况。结果治疗后治疗组各项临床症状改善较对照组明显:两组近期疗效比较无统计学意义(P>0.05);治疗组复发率明显低于对照组(P<0.05)。结论加味二仙汤能明显改善中老年女性慢性尿路感染的临床症状,降低复发率。

Objective To observe the clinical effects of modified “Erxian Decoction” combined with antibiotics in treating middle-aged and old women with chronic urinary tract infection （UTI） of kidney-yang insufficiency and residual evil. Methods Fifty-two subjects were randomly divided into two groups, 26 cases in each group. For the control group, full doses of sensitive antibiotics guided by the urine culture were given to complete a 14-day course of therapy for bacterial given orally every night for the following 6 weeks. For the taken orally twice a day for the following 6 weeks. Both near-future n; and during the remission period, small doses of antibiotics were group, in addition to antibiotics, modified “Erxian Decoction” was and long-term efficacy and the recurrence rates of UTI were observed Results After three courses of treatment, the clinical symptoms of treatment group were relieved significantly. There was no significant difference between the two groups in near-future efficacy. During the follow-up, the recurrence rate of treatment group was significantly lower than that of control group. Conclusion Modified “Erxian Decoction” can significantly alleviate the clinical symptoms and reduce the recurrent infection of UTI.