摘要
目的建立丹参舒心胶囊中丹参素钠的含量测定方法。方法色谱柱：Kromasil C18柱；流动相：乙腈-1．2％冰醋酸（9：91）；检测波长：280nm；流速：1.0mL·min^-1。结果丹参素钠线性范围为23．2～232μg·mL^-1，相关系数r为0．9997，回收率为98．96％，RSD为1．59％。结论本方法简便、可靠、重现性较好，能起到控制丹参舒心胶囊中丹参素钠含量的作用。
OBJECTIVE To establish an HPLC method for determination of danshensu sodium in Danshen Shuxin Capsule. METHODS Danshensu sodium in Danshen Shuxin Capsule was determined by HPLC,using Kromasil C18 column,acetonitrile-1. 2% acetic acid （9 ： 91） as mobile phase,the detection wavelength was 280nm. The flow rate was 1.0mL · min ^-1 RESULTS The linear range of danshensu sodium was ,93.2-232μg, mL ^-1,coefficient correlation rwas 0.9997,thc average recovery was 98.96 %, RSD = 1.59 %. CONCLUSION The method was simple, rapid, accurate and repreatablc. It can be used for determination of danshensu sodium in Danshen Shuxin Capsule.
出处
《齐鲁药事》
2008年第3期149-150,共2页
qilu pharmaceutical affairs
