2[2]Bekeredjian R,Chen S,Frenkel PA,et al.Ultrasound-targeted microbubble destruction can repeatedly direct highly specific plasmid expression to the heart[J].Circulation,2003,108(8):1022.
3[3]Wang XH,Liang HD,Dong B,et al.Gene transfer with microbubble ultrasound and plasmid DNA into skeletal muscle of mice:comparison between commercially available microbubble contrast agents[J].Radiology,2005,237(1):224-229.
4[4]Lentacker I,De Geest BG,Vandenbroucke RE,et al.Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA[J].Langmuir,2006,22(17):7273-7278.
5[5]Kondo I,Ohmori K,Oshita A,et al.Treatment of acute myocardial infarction by hepatocyte growth factor gene transfer-the first demonstration of myocardial transfer of a "functional" gene using ultrasonic microbubble destruction[J].J Am Coll Cardiol,2004,44(3):644-653.
6[6]Korpanty G,Chen S,Shohet RV,et al.Targeting of VEGF-mediated angiogenesis to rat myocardium using ultrasonic destruction of microbubbles[J].Gene Ther,2005,12(17):1305-1312.
7[7]Howard CM,Forsberg F,Minimo C,et al.Ultrasound guided site specific gene delivery system using adenoviral vectors and commercial ultrasound contrast agents[J].J Cell Physiol,2006,209(2):413-421.
8[8]Xenariou U,Griesenbach U,Liang HD,et al.Use of ultrasound to enhance nonviral lung gene transfer in vivo[J].Gene Ther,2007,14(9):768-774.
9[9]Guo DP,Li XY,Sun P,et al.Ultrasound-targeted microbubble destruction improves the low density lipoprotein receptor gene expression in HepG2 cells[J].Biochem Biophys Res Commun,2006,343(2):470-474.
10[10]Shimamura M,Sato N,Taniyama Y,et al.Development of efficient plasmid DNA transfer into adult rat central nervous system using microbubble-enhanced ultrasound[J].Gene,2004,11(20):1532-1539.
6Lindner JR, Dayton PA, Coggins MP, et al. Nonqnvasive imaging of inflammation by ultrasound detection of phagocytosed microbubbles [J]. Circulation, 2000,102(5) : 531-538.
7Unger E, Metzger P 3rd, Krupinski E, et al. The use of a thrombus-specific ultrasound contrast agent to detect thrombus in arteriovenous fistulae[J].Invest Radiol, 2000,35( 1 ) : 86-89.
8Lindner JR, Song J, Christian.sen J, et al. Ultrasound assessment of inflammation and renal tissue injury with microbubbles targeted to P-selectin[J]. Circulation, 2001,104(17) :2107-2112.
9Lawrie A, Brisken AF, Francis SE, et al. Microbubble-enhanced ultrasound for vascular gene delivery[J]. Gene Ther, 2000,7(23) : 2023-2027.
10Wang ZG, Ling ZY, Ran HT, et al. Ultrasound-mediated microbubble destruction enhances VEGF gene delivery to the infarcted myocardium in rats [J].Clin Imaging, 2004,28 (6) : 395-398.
5Sledge GW Jr. Vascular endothelial growth factor in breast cancer:Biologic and therapeutic aspects[J].Seminars in Oncology,2002,(3Suppl 11):104-110.
6Meijering BD,Henning RH,van Gilst WH. Optimization of ultrasound and microbubbles targeted gene delivery to cultured primary endothelial cells[J].Journal of Drug Targeting,2007,(10):664-671.doi:10.1080/10611860701605088.
7Dijkmans PA,Juffermans LJ,Musters RJ. Microbubbles and ultrasound:From diagnosis to therapy[J].European Journal of Echocardiography,2004,(04):245-256.