病理状态下的心肌缺血后适应

Ischemic postconditioning in the patients with pathological conditions

后适应是目前减少心肌缺血/再灌注损伤有效的干预措施,其机制也经逐步研究,逐渐清晰,具有深入的临床应用前景。但是冠心病的发生经常伴随着一些病理状态,如高脂血症、代谢综合征以及糖尿病、高血压等。因此,研究病理状态下心肌的后适应保护作用将具有更大的临床意义。

Postconditioning is an effective intervention in reducing ischemia - reperfusion injury at present, and it＇s mechanism become clear gradually. Clinical application prospects will be good. The occurrence of coronary heart disease associates with some pathological conditions, for example, hyperlipemia, metabolic syndrome, diabetes and hypertension etc. Thus, the study of cardioprotection by postconditioning in the patients with pathological conditions has profound clinical significance.