76例淋巴细胞性甲状腺炎合并甲状腺乳头状癌临床病理分析

Clinicopathological analysis of 76 cases of lymphocytic thyroiditis and thyroid papillary carcinoma

目的:探讨淋巴细胞性甲状腺炎合并甲状腺乳头状癌的临床病理特点。方法:对我院2004～2006年手术切除的572例淋巴细胞性甲状腺炎、甲状腺乳头状癌及淋巴细胞性甲状腺炎合并甲状腺乳头状癌的病理资料进行回顾性分析。结果:淋巴细胞性甲状腺炎、甲状腺乳头状癌及淋巴细胞性甲状腺炎合并甲状腺乳头状癌的平均发病年龄分别为45.2岁、43.3岁及39.9岁,均女性多于男性。甲状腺乳头状癌病例中有68例发生周围淋巴结转移(36%)。淋巴细胞性甲状腺炎合并甲状腺乳头状癌病例中19例发生周围淋巴结转移(25%)。淋巴细胞性甲状腺炎合并甲状腺乳头状癌的发病率占慢性淋巴细胞性甲状腺炎的19.9%,占甲状腺乳头状癌的28.6%。结论:淋巴细胞性甲状腺炎与甲状腺乳头状癌的关系密切,合并发生率较高(19.9%)。淋巴细胞性甲状腺炎合并甲状腺乳头状癌的周围淋巴结转移率(25%)低于单纯性甲状腺癌(36%)。提示淋巴细胞性.甲状腺炎合并甲状腺癌的预后要比单纯性甲状腺癌的预后好。

Objective.. To study the Clinicopathological characteristics of lymphocytic thyroiditis （LT） with thyroid papillary carcinoma （TPC） . Methods： 572 cases of LT and TPC and LT with TPC from 2004 to 2006 were reviewed. Results： The mean age respectively was 45.2, 43.3, and 39.9 in cases of LT and TPC and LT with TPC respectively. Female cases were more than male. 68 cases lymph-node metastases were found in the cases of TPC （36%）. 19 cases lymph-node metastases were found in the cases of LT with TPC （25%）. LT with TPC account for 19. 9% in the LT and 28. 6% in the TPC. Conclusions： LT was closely related with TPC,the incidence of LT with TPC was higher. So there was clinical meaning for paying more attention to these cases. The ratio of lymph-node metastases in LT with TPC showed less chance of lymph-node metastases than that of TPC. Therefore, the prognosis of LT with TPC was superior to TPC.