地塞米松、甘露醇治疗46例腰椎间盘突出症患者的急性腰腿痛

Treating acute Iumbago and scelalgia in 46 patients with prolapse of intervertebral disc with dexamethasone and mannitol

目的:探讨地塞米松、甘露醇治疗腰椎间盘突出症患者的腰腿痛症状的临床效果。方法:治疗组46例在用常规保守疗法措施的同时,另外给予地塞米松10mg溶于500ml 10％葡萄糖内静脉滴注,每天1次;20％甘露醇250ml,静脉快速滴注,每天2次。上述药物共使用3天。对照组仅用常规保守疗法治疗。结果:治疗组由于使用了甘露醇和地塞米松,病人的腰腿痛症状明显减轻,而且疼痛缓解的时间大多在2～3天后;而对照组在治疗3天后只有少数病人的腰腿痛症状有所缓解。结论:地塞米松和甘露醇对缓解腰椎间盘突出症病人的急性腰腿痛(发作2周内)疗效较明显,值得在临床中应用。

OBJECTIVE: To investigate the efficacy of treating symptoms of acute lumbago and scelalgin in patients with m-tervertebral disc lumbar prolapse. METHODS:In addition to conventional conservative treatment, 46 patients in treatment group were given intravenous infusion of dexamethasone 10 mg(in 500 ml 10% glusose)daily and rapid intravenous infusion of 20% man-nitol 250 ml twice daily. The above mdeicines were given for 3 days. The patients in control group received only conventional treatment. RESULTS:The symptoms of lumbago and scelalgia in patients of treatment group relieved significantly,mostly 2 - 3 days after treatment. While in controls,the symptoms relieved in only a few patients 3 days after. CONCLUSION:The efficacy of dexamethasone together with mannitol in the treatment of acute lumbago and scelalgia is significant. The drugs are worthwhile using.