头针对急性局灶性脑缺血模型大鼠的影响

Effects of Scalp Acupuncture on Focal Cerebral Ischemia in Rats

目的：探讨头针对大鼠局灶性脑缺血的治疗作用。方法：通过结扎大鼠一侧大脑中动脉（ｍｉｄｄｌｅｃｅｒｅｂｒａｌａｒｔｅｒｙｏｃｃｌｕｓｉｏｎ，ＭＣＡＯ）造成局灶性脑缺血模型，观察头针对体重、神经症状、被动性条件反射、血液流变性、脑梗塞面积及脑组织病理学指标影响。结果：头针能明显改善ＭＣＡＯ大鼠神经学症状，显著延长被动性条件反射潜伏期，减少错误次数，降低全血粘度，缩小脑梗塞面积，促进软化坏死灶内新生毛细血管和胶质细胞增生修复，减少坏死灶周围区脑组织水肿和炎症反应。结论：头针对局灶性脑缺血具有明显的治疗作用。

To observe the effect of scalp acupuncture on focal cerebral ischemia in rats. Methods: Focal cerebralischemia was produced in rats by the occlusion of right middle cerebral artery. The therapeutic action of scalpacupuncture on focal cerebral ischemia was studied by investigating the change of weight, neurologic symptoms, passive conditional reflex, hemorheology, infarct size of brain and pathology of brain tissue. Results: Scalp acupuncturecould not only improve obviously neurologic symptoms, prolong latent Period of the passive conditional reflex andlower blood viscosity, but also lessen infarct size, promote proliferation and repair of neogenetic capillary and gliocytein the malactic and necrotic regions and reduce the edema and inflammatory reaction around the necrotic region.Conclusion: Scalp acupuncture have therapeutic action on acute focal cerebral ischemia.