悬雍垂腭咽成形术对阻塞性睡眠呼吸暂停低通气综合征患者血液流变学的影响

Effects of uvulopalatopharyngoplasty on hemorheology in patients with obstructive sleep apnea hypopnea syndrome

目的:探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者UPPP对其血液流变指标的影响。方法:我院2004年2月～2006年2月确诊为中度或重度的OSAHS患者30例,AHI≤4011例,AHI>4019例,分别在术前及术后检测红细胞比容,全血黏度(高切变率、中切变率、低切变率),红细胞聚集数。结果:术后3～5个月复查红细胞比容以及全血黏度、红细胞聚集指数,较术前均显著降低(均P<0.01)。结论:通过UPPP治疗可以改善OSAHS的血液流变学的异常,降低OSAHS患者发生心脑血管疾病的危险性。

Objective：To observe the effect of UPPP on hemorheology in patients with obstructive sleep apneahypopnea syndrome （OSAHS）. Method.. Thirty patients of moderate or severe OSAHS were randomly selected from February 2004 to February 2006 in our hospital. Among them, 11 cases are moderate OSAHS （AHI〈40）, 19 cases are severe OSAHS （AHI〉40）. They were received uvulopalatopharyngoplasty. Whole blood specific viscosity, erythrocrit and erythrocyte aggregation index were detected before and after operation. Result：The values of testing in post operation were significantly lower than that in pre-operation （P〈0.01）, Conclusion.. Uvulopalatopharyngoplastyhas can improve abnormity of hemorheology of OSAHS and decrease the danger of cerebrovascular disorder.