腔隙性脑梗死与某些因素相关性的临床研究

Clinical research of certain related factors with acute cebral Infraction

目的探讨腔隙性脑梗死与某些因素的相关性,及发病前一过性缺血发作(TIA)发作是否对后继的腔梗具有保护作用。方法观察我院1996～2006年收治的腔隙性脑梗死的患者,收集发病的相关因素,并分为三组:A组:发病前无TIA发作;B组:发病前一周内有TIA发作;C组:发病前一周以上有TIA发作。入院后行常规治疗,并于入院时和一个月后分别进行NIHSS评分。结果在腔隙性脑梗死的患者中,高血压、糖尿病、高血脂、冠心病及TIA的比例较高,梗死前一周内有TIA发作的患者神经功能缺损情况好于其余两组(P<0.05)。结论对于腔隙性脑梗死,高血压、糖尿病、高血脂及冠心病是危险因素,TIA是预报因素,发病前一周的TIA对后继腔隙性脑梗死具有神经保护作用。

Objective To discuss the related factors with acute cebral Infraction , and whether transient ischemice attrack can play a protection role on acute cebral Infraction. Methods We observed the patients of acute cebral Infraction from 1996-2006 in our hospital and collect correlation factors,and divide it into three groups： A group, before the acute cebral Infraction, non-TIA outbreak; B group,a week before the acute cebral Infraction ,the TIA outbreak; C group, the preceding weeks before the acute cebral Infraction, the TIA outbreak. In hospital conventional therapy was carried on and at the same time NIHSS is made ,and a month later respectively. Results Among the acute cebral Infraction ,the patients with hypertension, diabetes, the high blood fats, coronary disease and the TIA die in a high rate, The protection role of B group was better than the other two （P 〈 0.05）. Conclusions Hypertension as well as diabetes, the high blood fats, coronary disease is dangerous factor and TIA is pridiction factor. TIA has a nerve protection role on acute cebral Infraction.