喷雾干燥法制备月见草油微球的工艺研究

Prepared evening primrose oil microspheres by spay drying

目的:探索喷雾干燥技术制备月见草油微球的最佳工艺参数。方法:利用气相色谱内标法测定γ-亚麻酸甲酯含量;以收率和包封率为指标,采用正交设计对喷雾干燥工艺参数进行优化。结果:最佳工艺参数为进料速度3mL·min-1,雾化压力100kPa,进风温度105℃。结论:月见草油微球质量符合预期要求;影响微球成型的主要因素为进料速度;喷雾干燥法制备月见草油微球工艺合理、可行。

Objective： To explore the best technique parameters on preparing evening primrose oil microspheres by spray drying technique. Method： GC and internal standard method were used to determine the content of γ-linolenie acid methyl esters, the teehnolngieal parameters were investigated by orthogonal experimental design with the yield and entrapment rate as indexes. Result： The charging rate as 3 mL · min^-1 , atomizing pressure as 100 kPa and the temperature of inlet as 105℃ were the best technique pa- rameters. Conclusion： Evening primrose oil mierospheres accorded with the expecting demand. The main influencing factor is the charging rate. Spray drying is reasonable and practical for preparing evening primrose oil mierospheres.