摘要
目的:探明消风散的抗变态反应的作用。方法:通过对大鼠颅骨骨膜肥大细胞脱颗粒的影响,观察消风散抗变态反应的作用及强度。结果:5.2g/kg和3.9g/kg剂量组消风散对大鼠颅骨骨膜肥大细胞脱颗粒的抑制率分别为(52.90±1.95)%和(46.25±2.96)%。结论:消风散能明显抑制大鼠颅骨骨膜肥大细胞脱颗粒,说明其有抗变态反应作用,为该药治疗荨麻疹提供了理论依据。
Objective:To explore the antiallergic effect of Xiaofengsan. Method By surveying the influence of Xiaofeng^n to rat skull periast mast cells degranulation, study the antiallergic effect and active strength of Xiao-feng-san. Result: The inhibition ratio of Xiao- feng-san to rat skull periost mast cells degranulation: 5.2 g/kg dose group (52.90 ± 1.95) %, 3.9g/kg dose group (46.25 ± 2. 96) %. Conclusion: Xiaofengsan notable inhibition to rat skull periost mast cells degranulation had proved its antiallergic effect, and provided theoretical base of its application to allergic rhinitis.
出处
《江西中医学院学报》
2008年第1期70-71,共2页
Journal of Jiangxi College of Traditional Chinese Medicine
基金
江西省卫生厅课题(赣卫中字2004[30]号)
关键词
消风散
肥大细胞
抗变态反应
Xiaofengsan
Mast cell
Anti-allergic effect