期刊文献+

慢性前列腺炎患者血清前列腺特异性抗原的检测及其意义 被引量:4

下载PDF
导出
摘要 目的:探讨血清前列腺特异性抗原(PSA)浓度变化在慢性前列腺炎发生、发展及疗效评价中的意义。方法:用ELISA法测定60例慢性前列腺炎患者(慢性前列腺炎组)直肠指检前的血清PSA浓度,以正常者30例为对照组,并对比慢性前列腺炎治疗前后患者血清PSA浓度的变化。结果:慢性前列腺炎组和对照组的血清PSA浓度分别为(1.6±0.3)和(0.5±0.2)μg/L,两组间差异有极显著性(t=11.68,P<0.01)。45例慢性前列腺炎治疗有效者,治疗后血清PSA浓度较治疗前明显下降(P<0.01),而15例治疗无效者,血清PSA浓度较治疗前下降不明显(P>0.05)。结论:慢性前列腺炎时血清PSA浓度明显升高,经治疗随着炎症的消失,PSA浓度可逐渐恢复正常,PSA浓度可作为慢性前列腺炎疗效评价的指标之一。
出处 《实用医学杂志》 CAS 2008年第6期961-962,共2页 The Journal of Practical Medicine
  • 相关文献

参考文献10

  • 1Wang M C, Valenzuela L A, Murphy G P. Pantication of human prostated specific antigen [J]. Invest Urol, 1979,179 (1) : 159- 161.
  • 2Shariat S F, Karam J A, Roehrborn C G. Blood biomarkers for prostate cancer detection and prognosis [ J ]. Future Oneol, 2007,3 (4) :449-461.
  • 3Mehrabi S, Ghafarian Shirazi H. Analysis of serum prostate- specific antigen levels in men aged 40 years and older in yasuj, iran [J]. Urol J, 2005,2(4) : 189-192.
  • 4Battikhi M N, Hussein I. Age-specific reference ranges for prostate specific antigen-total and free in patients with prostatitis symptoms and patients at risk [J]. lnt Urol Nephrol, 2006,38(3):559- 564.
  • 5Nadler R B, Humphrey P A, Smith D S. Effect of inflammation and benign prostatic hyperplasia on elevated serum prostate specific antigen levels [ J ]. J Urol, 1995,154(2 Pt 1 ) :407-413.
  • 6Morote J, Lopez M, Encabo G, et al. Effect of inflammation and benign prostatic enlargement on total and percent free serum prostatic specific antigen [ J ]. Ear Urol, 2000,37 ( 5 ) : 537-540.
  • 7Pansadoro V, Emiliozzi P, Defidio L. Prostate specific antigen and prostatitis in men under fifty [J]. Eur Urol, 1996,30( 1 ) :24-27.
  • 8Thompson I M, Ankerst D P. Prostate-specific antigen in the early detection of prostate cancer [ J]. CMAJ, 2007,176 (15) : 1853-1858.
  • 9MacLennan G T, Eisenberg R, Fleshman R L, et al. The influence of chronic inflammation in prostatic carcinogenesis:a 5- year foUowup study [J]. J Urol, 2006,176(3) : 1012-1016.
  • 10Sindhwani P, Wilson C M. Prostatitis and serum prostate-specifie antigen [J ]. Curt Urol Rep, 2005,6(4) : 307-312.

同被引文献17

引证文献4

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部