混合胶束催化N,N-二甲基甲酰胺碱性水解反应

MIXED MICELLAR CATALYZED ALKALINE HYDROLYSIS OF DIMETHYLFORMAMIDE

根据胶束催化反应的相分离模型和相关假定，建立了适用于胶束浓度［Ｍ］小于底物浓度［Ｓ］的混合胶束催化反应动力学方程．在４０℃下用热动力学模拟热谱曲线法，在表面活性剂复配（ＣＴＡＢ－Ｂｒｉｊ３５、ＳＤＳ－Ｂｒｉｊ３５、ＣＴＡＢ－Ｉｍ、ＳＤＳ－Ｉｍ、Ｂｒｉｊ３５－Ｉｍ）混合胶束溶液中及功能分子Ｉｍ溶液中，研究了ＤＭＦ碱性水解反应．应用作者使用的方程求得混合胶束与Ｉｍ催化的反应动力学参数ｋｍ，速率常数ｋｆ，结合常数Ｋ１与Ｋ。被研究的混合胶束和功能分子体系对该反应都有催化作用，讨论了催化作用的原因．

Based on the pseudophase model of micellar catalysis and some assumptions,the kinetic equations of mixed micellar catalysis have been drived in the case where reactant concentrations are higher than micellar concentrations in this paper.The alkaline hydrolysis of dimethylformamide(DMF) has been studied at 40℃ in the mixed micellar solutions (CTAB Brij35,SDS Brij35,CTAB Im,SDS Im,Brij35 Im) and in the solutions of functional molecule (1 benzyl 2 hydroxymethyl imidazole)(Im) with analog thermogram method of thermokinetics.The kinetic parameter k m in micellar pseudophase and the association constant of reactant with micelle K 1 ,and the kinetic parameter of functional molecular catalysis k f and the association constant of reactant with functional molecules K have been calculated with these kinetic equations,respectively.Alkaline hydrolysis of DMF is catalyzed by all researched mixed micelles and functional molecule.The authors suppose the micropolarity and local concentration effect of mixed micelles (CTAB Brij35,SDS Brij35) can account for the mixed micellar catalysis,mixed micelles which are consisted of Im with surfactants are somewhat like α chymotrypsin.