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卡维地洛与美托洛尔对缺血性心脏病疗效的对比分析 被引量:2

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摘要 目的:探讨卡维地洛与美托洛尔两种不同类型的β受体阻滞剂对缺血性心脏病心功能和心室重塑的影响。方法:将64例缺血性心脏病患者在常规治疗心力衰竭(心衰)基础上随机分为卡维地洛组(A组33例)和美托洛尔组(B组31例),应用超声心动图分别于治疗前、治疗6个月后测量左心室短轴缩短分数(FS),左心室射血分数(LVEF),舒张早期充盈峰速度(E峰),舒张晚期充盈峰速度(A峰),E/A、左心室重量指数和左心室球径指数。结果:①A组28例、B组27例用于分析。②两组治疗后,左心收缩功能、舒张功能及心室重塑各参数与治疗前比较,均有显著改善(P<0.05)。③治疗后LVEF在A组与B组比较差异有显著性(P<0.05);而FS、E峰、A峰和E/A两组比较差异无显著性(P>0.05)。④治疗后A、B两组的左心室重量指数和左心室球径指数比较差异有显著性(P>0.05)。结论:卡维地洛在改善左心室射血分数和心室重塑方面较美托洛尔更显著,治疗缺血性心脏病更优越。
作者 梁箐 孟刚
出处 《中国医药导报》 CAS 2008年第9期52-53,共2页 China Medical Herald
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