巯甲丙脯酸治疗小儿肺炎并心力衰竭疗效观察

Clinical observation of Captopril in the treatment of infantile pneumonia complicated with heart failure

目的:探讨巯甲丙脯酸治疗小儿肺炎并心力衰竭的临床疗效。方法:将56例肺炎并心力衰竭的患儿随机分为治疗组和对照组,治疗组36例,对照组20例,两组除采用常规治疗外,治疗组加用巯甲丙脯酸口服0.5-1.0mg/kg,8小时1次,最大量4mg/(kg·d)。结果:治疗组总有效率为97.2%,对照组总有效率为45.0%,两者比较P<0.05,差异有统计学意义。结论:巯甲丙脯酸治疗小儿肺炎并心力衰竭疗效好、副作用少,值得临床推广应用。

Objective：To study the clinical effect of Captopril in the treatment of infantile pneumonia complicated with heart failure.Methods： 56 cases of pneumonia complicated with heart failure patients were randomly divided into two groups,20 cases in the control group dealt with conventional treatment only;36 cases in treatment group dealt with Captopril orally 0.5-1.0 mg/kg every 8 hour,maximum 4 mg/（kg·d）.Results：The total effective rate of the treatment group was 97.2% ,while that of control group was 45.0%, significant difference was between two groups （P〈0.05）,Conclusion： Captopril has obvious effect in treatment of infantile pneumonia complicated with heart failure with few side effects, and it＇s worthy of clinic application.