摘要
多发性硬化(MS)是中枢神经系统常见的慢性炎症性自身免疫性疾病,目前病因及发病机制尚不清楚。近年研究发现,MS多种炎性细胞的钾离子通道参与了其自身免疫性发病过程,控制炎性细胞上钾离子通道为MS的治疗提供了新的途径。本文就MS自身免疫性炎症细胞上钾离子通道的研究进展作一综述。
Multiple sclerosis(MS) which has unknown aetiology and etiopathogenesis, is a chronic,autoimmune disease of the central nervous system(CNS). Recently, potassium channels in inflammatory cells were found to be involved in the immunopathogenesis of MS, and regulation of potassium channels provide a novel immuno- modulatory therapy in MS. This article reviewed the research development of potassium channels in MS.
出处
《国际内科学杂志》
CAS
2008年第3期151-154,共4页
International Journal of Internal Medicine
关键词
多发性硬化
钾离子通道
炎性细胞
Multiple sclerosis
Potassium channel
Inflammatory cell