桂林大阪两市新生儿脐带血和母乳中脂溶性维生素浓度比较

Fat soluble Vitamins in Cord Blood and Colostrum in Guilin and Osaka

为探讨婴儿佝偻病及新生儿出血症与微量营养素水平的关系，对桂林市哺乳妇女及新生儿脐带血进行了脂溶性维生素Ａ、Ｄ、Ｅ、Ｋ的测定，并与日本国大阪市哺乳妇女及新生儿作了对照比较。结果表明：脐带血和母乳中的维生素Ａ和Ｅ浓度在中日两国间无显著性差异。脐带血中的维生素Ｄ也无差异。但桂林市新生儿脐带血中β－胡萝卜素及玉米黄质显著低于日本大阪市新生儿，而ＰＩＶＫＡ－２值却明显升高，提示桂林市孕妇黄绿色蔬菜及水果的摄取不足。而较高的ＰＩＶＫＡ－２值则表明桂林市新生儿发生维生素Ｋ缺乏性出血症的危险性比日本大阪市要高。

To make out the relationship of micronutrient level with infantile rickets and hemorrhagic disease of newborn,fat soluble vitamins A,D,E,K and β carotene in the cord blood and colostrum of Chinese subjects in Guilin,China,were assayed and compared with those of Japanese subjects in Osaka,Japan.Vitamin A and E levels in the cord blood and colostrum of the Chinese group showed almost the same values as those of the Japanese group.There was also no significant difference in vitamin D level in cord blood between the two groups,while significantly lower levels of β carotene and cryptoxanthin,and a higher level of PIVKA 2(protein induced in absence of vitamin K) in cord blood were observed in the Chinese group.These findings pointed to a restricted intake of green yellow vegetables in the Chinese group and an increased risk of hemorrhagic disease of newborn of that group.