微波辐射无溶剂条件下三芳基吡喃盐的合成研究

A Study on the Synthesis and Reaction of 2,4,6-triarylpyrylium Salts in Absence of Solvent under Microwave Irradiation

本文在微波辐射无溶剂条件下,用芳香醛和芳香酮在三氟化硼乙醚催化下合成2,4,6-三芳基吡喃盐.分别考察了微波辐射功率,反应时间等对反应的影响,从而筛选出较佳反应条件.共合成十一种化合物.操作简便、提供了反应时间短、产率较高的合成三芳基吡喃盐环境友好的方法.

In this paper,we focused on the investigation of the reaction of different aldehyde with acetophenone under microwave irradiation and obtained 2, 4, 6-triarylpyrylium salts. 2, 4, 6- triarylpyrylium salts are very useful intermediates in synthetic organic chemistry and may be converted in good yields into other functional groups. On the basis of literature methods,we have obtained a large number of 2,4, 6-triarylpyrylium salts using one equivalent of substituted benzaldehydes I with two equivalents of substituted acetophenones 2 mediated by boron trifluoride etherate in the absence of solvent microwave irradiation conditions. The effect of microwave irradiation power, times on the reaction is investigated, we open a new simply, eco-friendly way for the synthesis of 2, 4, 6- triarylpyrylium salts.