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家族性脑海绵状血管畸形的分子遗传学机制

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摘要 脑海绵状血管畸形（CCM）系由单层血管内皮细胞构成的良性血管错构畸形，其间无常脑实质组织。大量尸体解部研究显示，脑海绵状血管畸形的发病率为0.10%-0.50%.临床主要表现为癫癎发作和脑出血，患者常有反复发作的脑出血病史，出血范围随累及血管数量的增加而逐渐扩大。
作者 苏立军 刘学伍 迟兆富 高国庆
机构地区 山东大学齐鲁医院神经内科
出处 《中国现代神经疾病杂志》 CAS 2008年第2期115-118,共4页 Chinese Journal of Contemporary Neurology and Neurosurgery
关键词 海绵状血管畸形 脑出血 遗传学机制 家族性 分子 细胞构成 血管内皮 实质组织
分类号 R782.2 [医药卫生—口腔医学] R743.34 [医药卫生—神经病学与精神病学]
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参考文献25

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二级参考文献12

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共引文献12

中国现代神经疾病杂志
2008年 第2期

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