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腹泻大鼠结肠水通道蛋白8表达的研究 被引量:12

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摘要 水通道蛋白(aquapofins,AQPs)是广泛存在于动植物细胞膜上转运水的特异性孔道。属膜蛋白大家族。到目前为止在哺乳动物中已发现了该家族的13个成员(AQP0~AQPl2)。AQP8是该家族的成员之一,已有研究表明其在结肠有大量的表达.但是腹泻时结肠AQP8表达情况的研究目前少见文献报道。本实验通过免疫组织化学对腹泻时结肠AQP8的表达进行定量定位研究,以明确AQP8在结肠水代谢中的作用,并进一步为腹泻相关性疾病的发病机制提供实验依据。
出处 《中国药物与临床》 CAS 2008年第4期295-297,共3页 Chinese Remedies & Clinics
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  • 1[1]Jain NK,Rosenberg DB,Ulahannan MJ,Glasser MJ,Pitchumoni CS.Sorbitol intolerance in adults.Am J Gastroenterol 1985;80:678-681
  • 2[2]Hyams JS.Chronic abdominal pain caused by sorbitol malabsorption.J Pediatr 1982;100:772-773
  • 3[3]Soergel KH.Colonic fermentation:metabolic and clinical implications.Clin Investig 1994;72:742-748
  • 4[4]Rambaud JC,Flourie B,Florent C.What is the status of fermentation diarrhoea? Rev Prat 1989;39:2598-2602
  • 5[5]Read NW,Miles CA,Fisher D,Holgate AM,Kime ND,Mitchell MA,Reeve AM,Roche TB,Walker M.Transit of a meal through the stomach,small intestine,and colon in normal subjects and its role in the pathogenesis of diarrhea.Gastroenterology 1980;79:1276-1282
  • 6[6]Ammon HV,Phillips SF.Inhibition of colonic water and electrolyte absorption by fatty acids in man.Gastroenterology 1973;65:744-749
  • 7[7]Islam MS,Sakaguchi E,Kashima N,Hoshi S.Effect of sugar alcohols on gut function and body compositions in normal and cecectomized rats.Exp Anim 2004; 53:361-371
  • 8[8]Tsukahara T,Ushida K.Succinate accumulation in pig large intestine during antibiotic-associated diarrhea and the constitution of succinate-producing flora.J Gen Appl Microbiol 2002;48:143-154
  • 9[9]Islam MS,Nishiyama A,Sakaguchi E.Rice gruel and rice starch reduce sorbitol-induced diarrhoea in cecectomized rats.Digestion 2005;72:13-2
  • 10[10]Beaugerie L,Nath SK,Desjeux JF.Glucose stimulates the absorption of sorbitol through the human jejunal mucosa.Gastroenterol Clin Biol 1989;13:379-382

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