摘要
采用廉价的氨基磺酸作为催化剂,芳香酮以及环己酮、3-戊酮与芳香醛、芳香胺可直接发生Mannich反应,生成相应的Mannich碱,产率均在60%～95%。氨基磺酸作为催化剂表现出高效的催化活性,优良的稳定性及良好的利用效率。
When sulfamic acid is used to catalyze the Mannich reaction of aromatic ketone （ nadone or 3-pentanone） with aromatic aldehydes and aromatic amines, the commensurate Mannich-bases can easily be obtained, and the product yield is in the range of 60% -95% .Sulfamic acid as an inexpensive solid catalyst with good stability can catalyze the reaction in high efficiency and also can be readily recycled and reused.
出处
《化学试剂》
CAS
CSCD
北大核心
2008年第4期277-279,共3页
Chemical Reagents
基金
国家973计划资助项目(2003CB716004)
