880例肝病患者死亡原因分析

Clinical analysis of 880 patients died from chronic liver diseases

目的探讨我院肝病患者的死亡原因及肝病种类的变化。方法总结2002年1月至2005年12月我院880例肝病死亡患者的临床资料,对性别、年龄、住院时间、肝功能、甲胎蛋白等37项指标进行统计分析。结果肝病死亡患者的病种构成中,肝硬化病死率从2002年的33.6%降至2005年的26.9%;而原发性肝癌病死率从2002年的37.5%上升至2005年的44.5%,但均无显著性差异。880例死亡患者合并3个以上并发症者占89.1%。结论□原发性肝癌已成为主要的肝病死亡类型,多种并发症共存是慢性肝病患者死亡的主要原因。

Objective To analyze the causes of death in patients with chronic liver disease and investigate the changes in the types of liver disease to provide reasonable prevention and treatment measures. Methods We retrospectively reviewed the data of 880 cases who died from chronic liver disease during Jan, 2002 to Dec, 2005 in our hospital. Results The mortality of liver cirrhosis decreased （from 33.6% in 2002 to 26.9% in 2005） and the mortality of primary liver cancer increased（ from 37.5% in 2002 to 44.5% in 2005）（P﹥0.05）. The mortality was 89.1% in patients who had three more complications. Conclusions Primary liver cancer has become the predominant type of chronic liver disease. The coexistence of a variety of complications in patients with chronic liver disease is the leading cause of death.