孕妇优生五项的检测与妊娠不良结局之间关系的探讨

Study on the measure of TORCH -IgM in pregnant women and the relationship with outcomes of abnormal fetus

目的:探讨孕妇优生五项(TORCH)特异性抗体IgM的检测与不良妊娠结局之间的关系。方法:应用酶联免疫吸附试验(ELISA)检测产前检查的孕妇血清中IgM抗体。结果:781例孕妇中CMV、TOX、RV、HSVI、HSVⅡ的阳性率分别为1·54%、1·79%、0%、2·94%、3·33%,781例TORCH-IgM总阳性率为9·5%。结论:孕妇TORCH-IgM项目的筛检,可作为近期感染的一个依据,对防止病原体所致的缺陷胎儿的出生,对于提高出生人口质量、落实少生优生的国策有着积极和重要的意义。

Objective： To investigate the measure of TORCH - IgM in pregnant women and the relationship with outcomes of abnormal pregnancy. Methods： The IgM in serum in prenatal examinations of pregnant women were detected by Enzyme - linked immunosorbent assay （ELISA） . Results： The s of CMV, TOX, RV, HSVI, HSV Ⅱ in 781 cases of pregnant women were 1.54% , 1.79%, 0% , 2.94% , 3.33% respectively, and the total positive rate in 781 cases was 9.5% . Conclusion： It is necessary to execute measuring of TORCH - IgM in pregnant women. The outcome of measuring can be a valuable clue to determine whether the TORCH infection among pregnant women has been occurred recently or not. It is important to control the production of abnormal fetus who was impaired by TORCH, improve the quality of newborn and implement the national policy.