单纯收缩期高血压与血清铁及影响因素分析

Association between isolated systolic hypertension and serum iron and risk factors

目的探讨血清铁与高血压的相关危险因素的交互作用及与单纯收缩期高血压的关系。方法采用整群抽样方法,抽取哈尔滨报社人群为调查对象,对该人群进行血压、身高、体重、腰围、臀围的测量及吸烟、饮酒的调查及血清铁的检测。结果单纯收缩期高血压组和非高血压组的年龄构成差异有统计学意义(P<0.01),性别构成差异无统计学意义(P>0.05);2组吸烟率、饮酒率差异无统计学意义(P>0.05)。2组血清甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)含量、空腹血糖、体质指数(BMI)、腰臀比(WHR)差异均有统计学意义(P<0.01)。未控制混杂因素时,血清铁和超重、空腹血糖对单纯收缩期高血压存在交互作用,但调整混杂因素后,不存在交互作用。结论血清铁与单纯收缩期高血压可能无关联。

Objective To explore the association between isolated systolic hypertension and the interaction between serum iron and risk factors. Methods The population of Harbin Newspaper Office were selected as subjects to conduct the cross - sectional study by cluster sampling. All subjects were interviewed with questionnaire and their blood pressure, stature, weight, waist circumference, hip circumference were measured and the status of smoking and drinking were investigated. Re. suits There was significant difference in age between the isolated systolic hypertensives and normotensives （P 〈 0.01）, but not in gender（P 〉 0.05）. The prevalence of alcohol drinking and smoking had no significant difference in two groups（ P 〉 0.05）. The average levels of TG, TC, LDL- c, fasting plasma glucose （FPG） in isolated systolic hypertensives were higher than in the norrnotensives（ P 〈 0.01 ）. Both the body mass index （BMI） and ratio of waist to hip circumference （WHIR） were significantly higher in the isolated systolic hypertensives than in the norrnotensives （ P 〈 0.01 ）. Positive interaction between serum iron and overweight was found, it was similar in serum iron and fasting plasma glucose （FPG）. This interaction was confined to no confounding factors being adjusted. Conclusion Serum iron was not associated with isolated systolic hypertension.