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小分子受体酪氨酸激酶抑制剂—拉帕替尼 被引量:3

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出处 《河北医药》 CAS 2008年第3期394-395,共2页 Hebei Medical Journal
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参考文献8

  • 1Hegde PS, Rusnak D, Bertiaux M, et al. Delineation of molecular mechanisms of sensitivity to lapatinib in breast cancer cell lines using global gene expression profiles. Molancer Therapeutics, 2007,6:1629-1640.
  • 2Nahta R,Yuan LX, I)u Y, et al. Lapatinib induces apoptosis in trastuzumab- resistant breast cancer cells: effects on insulin-like growth factor Ⅰ signaling. Mol cancer ther, 2007,6:667-674.
  • 3Burris HA 3rd, Hurwitz HI, Dees EC, et al. Phase Ⅰ safety, phannacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas. J clin oncol, 2005, 23: 5305- 5313.
  • 4Howard A, Burris I,Herbert I,et al.Phase I ssfety pharmacokinetics and clinical activity study of lapatinib ( GW572016 ), a reversible'dual inhibitor of epidermal grontor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas. J Clin Oneology, 2005, 23 : 5305-5313.
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  • 6Midgley RS, Kerr DJ, Flaherty KT, et al. A phase Ⅰ and phannacokinetic study of lapatinib in combination with infusional 5-fluorouracil, leucovorin and irinotecan, Ann Oncol, 2007,18:2025-2029.
  • 7Agulnik M, Cohen EW, Cohen RB, et al. Phase Ⅱ study of lapatinib in recurrent or metastatic epidermal growth factor receptor and/or erbB2 expressing adenoid cystic carcinoma and non adenoid cystic carcinoma malignant tumors of the salivary glands. Journal of clinical oncology, 2007,25 : 3978-3984.
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同被引文献16

  • 1徐兵河.乳腺癌分子靶向治疗的研究进展[J].中国处方药,2006,5(8):38-41. 被引量:3
  • 2刘斯婕,胡春.拉帕替尼(lapatinb)[J].中国药物化学杂志,2007,17(5):333-333. 被引量:7
  • 3美国食品药品监督管理局批准的甲苯磺酸拉帕替尼片处方信息[EB/OL].[2014-03-10].http://www.accessdata.fda.gov/drugsatfda-.docs/label/2013/022059s016s0171b1.pdf.
  • 4欧洲药品监督管理局对甲苯磺酸拉帕替尼片的评估报告[EB/OL].[2014-03-10].http://www.ema.europa.eu/docs/en-GB/document-library/EPAR---Public-assessment-report/human/000795/WC500044960.pdf.
  • 5欧洲药品监督管理局人用药品评价委员会关于基因毒性杂质限度指南[EB/OL].[2014-03-10].http://www.ema.europa.eu/docs/en-GB/doeument~library/Scientific-guideline/2009/09/WC500002903.pdf.
  • 6澳大利亚治疗药物监管局对甲苯磺酸拉帕替尼的评估报告[EB/OL].[2014-03-10].http://www.tga.gov.au/auspar/auspar-lapatinib.
  • 7国家食品药品监督管理局进口注册标准[S].2008.
  • 8欧洲药品监督管理局对甲苯磺酸拉帕替尼片的评估报告[EB/0L].[2014-03-10].http://www.ema.europa.eu/docs/en-GB/document-library/EPAR-Public-assessment-report/hu-man/O00795/WC500044960.pdf.
  • 9国家食品药品监督管理局进口注册标准[S].2008.
  • 10林德娟,李隆弟.荧光胺与芳伯胺衍生反应的介质效应[J].光谱学与光谱分析,1997,17(3):10-15. 被引量:8

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