摘要
目的考察注射用盐酸川芎嗪的配伍稳定性。方法模拟临床浓度和使用方法,采用HPLC法测定注射用盐酸川芎嗪与果糖等5种常用输液配伍后的含量变化,同时测定溶液的pH值,观察溶液的颜色及澄明度的变化。结果注射用盐酸川芎嗪与果糖等常用输液配伍后,各项结果在8h内均无明显变化。结论注射用盐酸川芎嗪可与果糖等常用输液配伍使用。
OBJECTIVE To study the compatible stability of Ligustrazini hydrochloridi injection. METHODS The pH value of the solution was tested, the solution content was determined by HPLC, the colour and clarity was observed to study the stability of Ligustrazini hydrochloridi injection with common infusions. RESULTS There was no significant changes after matching for eight hours.CONCLUSION Ligustrazini hydrochloridi injection can combine with common infusions.
出处
《海峡药学》
2008年第3期26-28,共3页
Strait Pharmaceutical Journal
关键词
注射用盐酸川芎嗪
输液
配伍
稳定性
Ligustrazini hydrochloridi injection
Infusion
Compatibility
Stability