不同出生体重儿3月龄骨发育状况分析

A analysis of bone development of infants aged 3 months old with different birth weight

目的了解不同出生体重儿3月龄的骨发育状况,为更好的指导不同出生体重儿早期改善骨营养提供理论依据。方法分析对比3组不同出生体重儿3月龄时胫骨超声传播速度、体重、身长、头围、3月龄与出生时的体重差、身长差等资料。结果在女婴,3组间胫骨超声传播速度比较差异有统计学意义(F=4.471,P<0.05);在男婴,3组间胫骨超声传播速度比较未见统计学差异(F=2.264,P>0.05);对3组不同出生体重儿3月龄时的体重、身长、头围及体重差、身长差进行比较,差异有统计学意义(P<0.01);将以上若干因素拟合成多元回归方程进行多元回归分析提示方程有意义,其中体重差的影响最大(负相关),其次为现身长(正相关)。结论宫内良好的营养状况有利于婴儿早期的骨量积累;体重增长过快可能影响婴儿早期的骨量积累,应重视低出生体重儿的早期营养并积极干预。

Objective To investigate bone development of infants aged 3 months old with different birth weight so as to provide theoretical basis for improving osteotrophy in early infancy. Methods The speed of sound （SOS） in tibiae, body weight, body length, and head circumference, increments in body weight and body length between birth and3 months of age of infants in different birth weight groups were analyzed and compared. Results For female infants, there are significant differences between the three groups in SOS in tibiae（ F--4. 471, P 〈0.05） ,while for male infants, in SOS in tibiae there were no significant differences between the three groups（ F =2. 264,P 〉0.05）. In body weight, body height, head circumference at 3 moths of age and increments in weight and height, there were significant differences between 3 different birth weight groups （ all P 〈0. 01 ）. Multiple regression analysis showed that the increment in body Weight was the most important influential factor of bone mineral and it was negatively related with bone mineral, the next was current body length, it was positively with bone development. Condusion Good intrauterine nutrition is helpful to accumulation of bone mineral in early infancy, while overgrowth in body weight might affect accumulation of bone mineral in early infancy. So, more attention should be paid to nutrition in early infancy of those infants with low birth weight and active interventions should be given for them.