摘要
乳腺癌是女性最常见的恶性肿瘤之一,近年来发病率逐年增高,内分泌治疗是乳腺癌最重要的治疗方法之一。第三代芳香化酶抑制剂的研发使用是当前乳腺癌内分泌治疗的重大进展。他莫昔芬(TAM)曾是早期乳腺癌辅助内分泌治疗的金标准药物,但现在它正日益受到第三代芳香化酶抑制剂的挑战,正是由于第三代芳香化酶抑制剂疗效的显著性和副反应的易控性,它正取代TAM的地位,被一些国家及国际临床指南推荐为绝经后雌、孕激素受体阳性患者的首选治疗药物。现对乳腺癌芳香化酶抑制剂治疗新进展作一综述。
出处
《浙江医学》
CAS
2008年第3期301-303,共3页
Zhejiang Medical Journal
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