慢性阻塞性肺疾病急性加重期中医证候规律的初步探讨

Preliminary Investigation of Traditional Chinese Medical Syndromes in Acute Exacerbation Chronic Obstructive Pulmonary Disease

【目的】探讨慢性阻塞性肺疾病(COPD)急性加重期中医证候规律。【方法】在文献调研基础上构建中医证候调查表,采用横断面调查方法收集100例COPD急性加重期患者的人口学信息、中医证候信息和理化检查资料。【结果】"肺脾气虚、痰瘀阻肺","肺脾肾虚、痰饮瘀肺","肺脾气虚、痰热瘀肺","气阴两虚、痰热瘀肺"4种证型为COPD急性加重期主要证型,分别占34.3%、15.2%、26.3%、24.2%。是否合并肺心病、右心衰在4种证型间的分布有显著性意义(P<0.05)。【结论】COPD急性加重期中医证型多为复合证型,其分布规律体现了"气虚痰瘀"的基本病机。

Objective To investigate the traditional Chinese medical（TCM）syndromes in acute exacerbation chronic obstructive pulmonary disease（AECOPD）.Methods Based on literature review,a TCM questionnaire was established.Cross-sectional study was adopted,and demographic information,TCM syndrome data and physiochemical examination results were collected.Results The main TCM syndrome types are：phlegm-stasis blocking lung due to deficiency of lung and spleen Qi（34.3%）,phlegm and fluid retention in lung due to deficiency of lung,spleen and kidney（15.2%）,phlegm-heat accumulation in lung due to deficiency of lung and spleen Qi（26.3%）,and phlegm-heat accumulation in lung due to deficiency of Qi and yin（24.2%）.The incidences of complications of pulmonary heart disease and right ventricular failure had statistical significance between the syndrome patterns（P〈0.05）.Conclusion The syndromes of AECOPD are characterized as complex patterns,which reflects the basic pathogenesis of phlegm accumulation due to deficiency of Qi.