晚期肿瘤并发呼吸道感染70例痰培养临床分析

Clinical analysis of sputum cultures in 70 patients with advanced tumors complicated with respiratory infection

目的:探索晚期肿瘤患者并发呼吸道感染的特点。方法:针对不同的肿瘤患者,根据病情对口腔分泌物进行痰培养,检测并鉴定致病菌。70例患者中:男44例,女26例;年龄>60岁48例,50～60岁12例,<50岁10例。结果:晚期肿瘤患者并发呼吸道感染中G^-菌阳性率54.2%,G^+菌阳性率14.3%,真菌感染的阳性率为31.4%。结论:晚期肿瘤患者呼吸道较常见的感染致病菌种为真菌、肺炎克雷伯菌、鲍曼不动杆菌、大肠杆菌和铜绿假单胞杆菌,发病年龄主要集中在60岁以上男性患者。因此对于晚期肿瘤患者,应根据病情实时、正确留取标本,进行病原体检测并结合既往用药史,选择合理的治疗方案。

Objective ： To study the features of microbes in respiratory infection patients with advanced tumors. Methods ： Culture of sputum was taken from the mouth cavity in light of the condition of the patients for determining the pathogenic microbes. Of the 70 cases, 44 of them were male and 26, female. 48 cases aged more than 60 years, 12 ranged in age from 50 to 60 years and 10 were younger than 50 years. Results ： In 70 advanced tumor patients complicated with respiratory infection, microbes of gram-negative bacilli were detected in 54.2% cases, grampositive in 14.3% cases and fungi infection in 31.4%, respectively. Conclusion： Most common pathogenic microbes that affect patients of advanced tumor with respiratory tract infection are fungi, Klebsiella pneumoniae, Acinetobacter baumannii, Escherichia coils and Pseudomonas, and the male patients aged 60 years and over are easily involved. Consequently, the treatment prescription has to be centered on the real condition, right examination of culture and pathogenic microorganism and past medication history.