摘要
K562细胞作为体外研究白血病细胞增殖与分化的良好模型,其转录因子及作用机制研究是一关键的环节。本文就其中GATA、STAT、Sp家族等在K562细胞增殖分化中的作用及其相关进展作一综述。
Leukemic cell line K562 is a good model to investigate proliferation and differentiation of leukemic cell. Mechanism of transcription factor is a key link of the investigation. In this paper, the progress and role of GATA, STAT in proliferation and differentiation ofK562 were reviewed.
出处
《现代生物医学进展》
CAS
2008年第4期744-746,771,共4页
Progress in Modern Biomedicine
基金
国家自然科学基金(No.30300449)
国家中医药管理局研究课题(No.02-03ZP52)
关键词
K562细胞
转录因子
增殖分化
K562 cell
transcription factor
proliferation
differentiation