摘要
脂蛋白脂酶(lipoprotein lipase,LPL)是脂质代谢的关键酶,主要水解甘油三酯,在乳糜微粒及极低密度脂蛋白的代谢中发挥重要作用。该酶的缺乏或活力异常,与血脂异常、代谢综合症、动脉粥样硬化、糖尿病、子痫前期等疾病有一定关系。一些具有调脂作用的中药能够影响脂蛋白脂酶的活力或表达。
Lipoprotein Lipase （LPL） is the key enzyme in the metabolism of lipids ,which mainly hydrolyzes triglyceride （TG） and plays an important role in the metabolism of chylomicrons （CM） and very low density lipoprotein （VLDL）, The defect of LPL or its abnormal activity is related to lipid abnormality ,metabolism syndrome, atherosclerosis, diabetes, pre-eclampsia and so on. Some traditional Chinese herbal medicines have the effects of regulating lipids can influence the activity or expression of the lipoprotein lipase,
出处
《现代生物医学进展》
CAS
2008年第4期750-753,共4页
Progress in Modern Biomedicine
关键词
脂蛋白脂酶
血脂
代谢综合症
动脉粥样硬化
中药
Lipoprotein Lipase
Lipid
Metabolism Syndrome
Atherosclerosis
Traditional Chinese herbs
