摘要
目的探讨非小细胞肺癌伴单发脑转移瘤的外科治疗及预后。方法回顾我院1991年1月至2002年1月收治的56例非小细胞肺癌伴单发脑转移瘤患者临床资料,脑转移瘤伽马刀治疗后均行肺癌根治术,术后常规化疗和全脑放疗,并评估疗效。结果本组患者均无严重手术并发症,1年生存率为73.5%(36/49),3年34.7%(17/49),5年16.3%(8/49),中位生存期20.5个月。结论非小细胞肺癌伴单发脑转移瘤外科治疗可以延长患者的生存期和提高治疗效果。
Objective To investigate the clinical value of surgical treatment and prognosis for non- small cell lung cancer with isolated cerebral metastasis. Methods From January 1991 to January 2002, fifty-six patients diagnosed as non-small cell lung cancer with isolated cerebral metastases received treatment in our hospital. The management consisted of cerebral gamma knife radiosurgery, lung cancer resection, whole brain irradiation and chemotherapy. The short-time and long-time outcomes were evaluated. Results No severe complications occurred in these cases. The 1-, 2- and 5-year survival rates were 73.5% （36/49）, 34. 7% （17/49） and 16. 3% （8/49） respectively. The median survival time （MS） of the patients was 20. 5 months. Conclusion The outcome of surgical treatment in patients of non-small lung cancer with isolated brain metastases is favorable ,which can prolong the survival time and improve the therapeutic efficacy.
出处
《中国肿瘤临床与康复》
2008年第2期144-145,共2页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
肺肿瘤/外科学
脑转移
Lung neoplasms/surgery
Cerebral metastasis
