柯萨奇B组病毒感染相关性急性横贯性脊髓炎—附7例临床分析

Acute transverse myelitis associated with Coxsackievirus B-A retrospective analysis of 7 patients

目的本研究通过对柯萨奇病毒感染相关性急性横贯性脊髓炎（ATM）的发病机制进行探讨，以期开展进一步的病因学研究。方法通过回顾性分析，对近十年我科明确诊断的33例ATM病例进行研究。结果发现有7例患者血清柯萨奇B组病毒IgMAb阳性，而且未发现其他病原生物感染的证据。结论柯萨奇B组病毒感染所致的ATM的发病机制有可能存在着病毒的直接感染。

Objective The present study aimed to understand possible relationship between Acute transverse myelitis（ATM） and infection with Coxsackievirus B. Methods IgM antibody against Coxsackievirus B was detected in cerebrospinal fluid of 33 patients with ATM. Results In 7 of the 33 cases with ATM, the IgM andtibody Coxsackievirus B （CVB） was positive. No infections with other pathogens were found at the onset of the disease. Conclusions The pathogenesis of ATM may involve infection with Coxsackievirus B.