摘要
目的:筛选利胆化瘀片的最佳水煎提取工艺。方法:以出膏量及槲皮素和山柰素总量作为考察指标,采用L9(3^4)正交表进行筛选,考察了加水量、煎煮时间、煎煮次数等因素以确定最佳的提取工艺。结果:煎煮次数对提取效果的影响最明显,最佳工艺为加10倍水量、每次煎煮1.5h、煎煮3次。结论:该试验所优选的工艺稳定、可靠,可用于实际生产制备。
Objective: TO optimize the extraction process and condition of Lidanhuyu tablets. Method: The factors of affecting extraction of effective ingredients including the added amount of water, the extracting time and times of extraction were studied by L9 (3^4 ) orthogonal design with the yield of dry extract and the total count of quercitrin and kaempferol were observed as the indicator. Result: The times of extraction were the most significant factor, and the optimal extraction process and condition of Lidanhuyu tablets were 3 times extraction, 1.5 h for extraction process and 10 times amount of water. Conclusion: The experiment results showed that the extraction process and condition were stable and reliable.
出处
《中国药师》
CAS
2008年第4期378-380,共3页
China Pharmacist
基金
武汉市技术创新与产业化重大专项攻关课题(项目编号:2002600513415)
关键词
利胆化瘀片
提取工艺
正交设计
槲皮素
山奈黄素
Lidanhuayu tablets
Extraction process
Orthogonal design
Quercitrin
Kaempferol