小柴胡汤防治肝病机制研究进展

Advances in mechanisms of Xiao Chaihu Tang preventing and treating liver diseases

小柴胡汤是《伤寒论》中著名方剂.许多实验研究和临床实践已经表明,他可以通过多个途径阻断由肝炎至肝纤维化再至肝癌的发展过程,对肝病防治具有重要意义.小柴胡汤防治肝病的机制包括抑制肝炎病毒的复制、抗肝炎病毒活性、保护肝细胞膜、防治肝损伤、多途径抑制肝纤维化、免疫调节和抗肿瘤作用等.

Xiao Chaihu Tang is a famous prescription in ＂Shanghanlun＂. Experimental studies and clinical practices have proved that it is effective in the treatment of liver diseases because it can block the development of hepatitis to liver fibrosis, and further to liver cancer through various pathways. The mechanisms of Xiao Chaihu Tang treating liver diseases include： inhibiting the replication of hepatitis virus, protecting liver cells, preventing liver damage, and suppressing liver fibrosis as well as immune regulation and anti-tumor effect, etc.