盐酸坦洛新治疗慢性前列腺炎临床研究

A clinical survey of Tamsulosin Hydrochloride sustained release pieces in the treatment of chronic prostatitis

目的探讨盐酸坦洛新缓释片治疗慢性前列腺炎的临床效果。方法79例慢性前列腺炎的患者随机分成两组。A组41例,采用左氧氟沙星0.4g,1次/d,静脉滴注,2周后改用左氧氟沙星0.2g口服,2次/d,萘普生缓释胶囊2粒/次,1次/d,加盐酸坦洛新缓释片0.2mg/次,2次/d。B组38例,采用左氧氟沙星0.4g,1次/d,静脉滴注,2周后改用左氧氟沙星0.2口服。2次/d,采用萘普生缓释胶囊2粒/次,1次/d。4周为一个疗程,治疗时间为两个疗程。随访3～11个月,详细记录治疗过程中的症状、体征、EPS常规和尿常规。结果A组41例,其中治愈23例(56.10%),显效13例(31.70%),总有效39例(总有效率87.80%),无效5例(12.20%)。B组38例,其中治愈11例(28.95%),显效13例(34.21%),总有效24例(总有效率63.16%),无效14例(36.84%)。A组与B组在治愈率、总有效率两方面比较均有统计学意义。结论盐酸坦洛新治疗慢性前列腺炎有较满意的临床疗效。

Objective To evaluate the validity of selective adrenoreceptor antagonists （Tamsulosin Hydrochloride sustained release piece） in the treatment of chronic prostatitis. Methods 79 cases of chronic prostatitis were randomly divided into group A treated wht finasteride （41 cases） or control group B（38 cases）. Group A was given Tamsulosin Hydrochloride sustained release piece, Antibiotics and Naproxen. Group B Antibiotics and Naproxen only. Routine treatment was carried out 8 weeks in all of the 79 cases. Results In group A the curative rate was 56.10% and the remarkable effective rate 31.70%.the total effective rate being 87.80%. In group B they were 28.95%, 34.21%, 63.16%, 36.84% respectively. The curative rate and the total effective rate of group B were lower than group A （P〈0.05）. Conclusion Tamsulosin Hydrochloride sustained release piece can be recommended for the treatment of symptomatic chronic prostatitis.